BridgeBio Pharma is seeking a Senior Clinical Trial Manager to drive the execution and management of an imaging study for acoramidis (AG10). You will be responsible for ensuring studies are completed on time, with high quality, and in full compliance with Good Clinical Practices (GCP). Your leadership will directly contribute to achieving key corporate milestones.

What You'll Do

Lead the Clinical Study Team for assigned projects, from concept to protocol, achieving key milestones like First Patient In and Database Lock.
Manage external vendors, contract research organizations, and potentially internal resources like Clinical Research Associates (CRAs) and Clinical Trial Assistants.
Prepare, review, and approve essential study documents including the Monitoring Manual, Study Operational Manual, and Source Data Verification Plan.
Coordinate and design study materials such as case report forms (CRFs), patient diaries, and source documents.
Manage operational activities and monitoring at clinical study sites to ensure adherence to GCP, SOPs, and protocols.
Negotiate and manage vendor work agreements and site contracts.

What We're Looking For

A Bachelor’s degree in a scientific discipline or equivalent.
At least eight years of relevant biopharma industry experience (biotech, pharmaceutical, CRO, or medical device).
At least two years of direct experience managing clinical trials.
Proven vendor management experience within clinical operations/development.
Strong verbal and written communication skills, with the ability to convey strategic direction clearly.
Ability to build and maintain strong working relationships cross-functionally to meet project goals.
Proficiency with the Microsoft Office Suite (Word, Excel, Project, Outlook).
Willingness and ability to travel periodically.

Nice to Have

An advanced degree.

Technical Stack

Microsoft Office Suite: Word, Excel, Project, Outlook.

Team & Environment

You will lead the Clinical Study Team for assigned projects and may manage internal resources such as Clinical Research Associates (CRAs) and Clinical Trial Assistants (CTAs).

Benefits & Compensation

Compensation range: $162,700 - $191,000 USD.
Market-leading compensation and comprehensive health care with 100% premiums covered for you and dependents.
401K with 100% employer match on first 3% & 50% on the next 2%.
Employee stock purchase program and pre-tax commuter benefits.
Referral program with a $2,500 award for hired referrals.
Mental health support via Spring Health (6 therapy & 6 coaching sessions).
Hybrid work model with autonomy in where and how you work.
Unlimited flexible paid time off and paid parental leave (4 months for birthing parents & 2 months for non-birthing parents).
Flex spending accounts and company-provided group term life & disability insurance.
Subsidized lunch via Forkable on office days.
Career development via LinkedIn Learning, LifeLabs, Spring Health, BetterUp Coaching, and internal mobility opportunities.
Strong performance is celebrated with financial rewards, peer recognition, and growth opportunities.