USA - Quincy, MA On-site Employment USD 79,000 – 95,000 / year

Twist Bioscience is hiring a Research Associate II – Antibody Characterization

Responsibilities

  • Conduct titer assessments, antibody screening, and validation using high-throughput multicolor flow cytometry and ELISA methods
  • Execute and resolve issues in cell-based functional assays
  • Maintain mammalian cell cultures, including thawing, passaging, scaling up, freezing, and quality control for diverse adherent and suspension cell lines
  • Design, implement, and troubleshoot antibody characterization experiments using label-free technologies such as BLI and SPR to analyze binding kinetics, ligand interference, and epitope binning
  • Manage sample processing, track inventory, and support automation integration within the team
  • Carry out multiple concurrent antibody discovery projects involving hands-on laboratory work, data interpretation, reporting, and timely delivery of results
  • Document experimental procedures accurately, draft technical reports, and share findings with scientific rigor and ethical standards

Responsibilities

  • Conduct titer assessments, antibody screening, and validation using high-throughput multicolor flow cytometry and ELISA methods
  • Execute and resolve issues in cell-based functional assays
  • Maintain mammalian cell cultures, including thawing, passaging, scaling up, freezing, and quality control for diverse adherent and suspension cell lines
  • Design, implement, and troubleshoot antibody characterization experiments using label-free technologies such as BLI and SPR to analyze binding kinetics, ligand interference, and epitope binning
  • Manage sample processing, track inventory, and support automation integration within the team
  • Carry out multiple concurrent antibody discovery projects involving hands-on laboratory work, data interpretation, reporting, and timely delivery of results
  • Document experimental procedures accurately, draft technical reports, and share findings with scientific rigor and ethical standards
About company
Twist Bioscience

Twist Bioscience is a leading synthetic biology company that accelerates drug discovery and development by decoding the code of life. The company leverages its proprietary silicon-based synthetic DNA manufacturing platform to produce high-quality genes, oligo pools, and variant libraries at scale.

Twist serves a broad range of applications in life sciences, including next-generation sequencing (NGS), antibody discovery, and biopharma development. Its products support researchers in genomics, agriculture, drug development, and diagnostics, enabling faster and more efficient scientific breakthroughs.

The company offers a comprehensive portfolio including NGS target enrichment panels, synthetic controls, library preparation kits, and antibody discovery solutions. Through its Twist Biopharma and antibody optimization services, it supports partners in developing therapeutic candidates with enhanced properties.

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Job Details
Department Antibody Characterization
Category other
Posted 21 days ago