We are seeking a motivated individual to join our team and expand our antibody characterization department. Using state-of-the-art technologies and workflows, this Research Associate would work with the Antibody Characterization team to ensure project-specific deliverables are met across a diverse panel of discovery campaigns and contract services. The role would involve wet-lab experimental design, execution, and data analysis for multiple custom antibody development projects, incorporating various biologics assay formats
What you will be doing
- Performing titer testing, screening, and antibody validation by high-throughput multicolor flow cytometry and ELISA
- Running and troubleshooting cell-based functional assays
- Performing mammalian cell culture, including thaw, maintenance, expansion, cryopreservation, and QC of a wide variety of adherent and suspension cell lines
- Developing, running, and troubleshooting antibody characterization experiments using advanced label-free analytical techniques (e.g., BLI and SPR) in a variety of formats to evaluate binding kinetics, ligand blocking, and binning
- Sample handling, sample inventory tracking, and assisting with automation integration into the department
- Concurrently execute multiple antibody discovery projects requiring wet lab activities, data analysis, report generation, and preparation of deliverables adhering to project timelines
- Record and communicate experimental details, draft reports, and deliver data with a high level of integrity and ethics
What You’ll Bring to the Team
- Bachelor's degree in molecular biology, biochemistry, or a related discipline, and a minimum of 2 years of related experience; or a master’s degree without experience; or equivalent work experience.
- Excellent aseptic technique and experience with mammalian adherent and suspension cell culture are required
- Flow cytometry experience is required
- Ability to troubleshoot scientific processes
- Ability to work independently, but also collaborate and effectively communicate within and across departmental team
Exceptional written and verbal communication skills
- Highly organized, detail oriented and able to operate in a fast-paced and growing environment
- Industry experience strongly preferred.
- Understanding of antibody discovery, preferably focusing on assay development and protein characterization, is preferred
- Previous experience with Carterra, Octet, Hamilton, and/or iQue instruments nice to have
- Direct experience with ELISA preferred