Toon City, JP On-site Employment ¥3.50m - ¥4m

Optieum Biotechnologies is hiring a Research Assistant, Pre-clinical research

Responsibilities

  • Assist with routine molecular biology tasks under supervision, including DNA/RNA extraction, cDNA synthesis, PCR, and plasmid preparation.
  • Support plasmid preparation workflows (e.g., mini-preps, bacterial transformation) following established protocols.
  • Assist in cell culture maintenance, including handling of Jurkat cells, antigen-expressing cell lines, and other mammalian cell lines.
  • Support the preparation of reagents, media, and materials required for Eumbody experiments.
  • Assist with viral transduction experiments and downstream cell handling under guidance.
  • Support flow cytometry experiments, including sample preparation and data acquisition, following predefined gating and analysis guidelines.
  • Assist with cell sorting-related preparation tasks under supervision.

Requirements

  • You MUST be fluent in English. Please provide your resume in either English or Japanese.
  • You MUST already be located in Japan.
  • Bachelor’s or Master’s degree in Biology, Molecular Biology, Biotechnology, or a related field.
  • Basic hands-on experience with molecular biology or cell culture techniques (academic laboratory experience acceptable).
  • Willingness to follow protocols carefully and work under supervision.
  • Strong attention to detail and commitment to accurate documentation.
  • Good communication skills and a collaborative mindset.

Nice to Have

  • Prior experience in a research laboratory environment (academic or industry).
  • Familiarity with basic mammalian cell culture.
  • Interest in immunology, cancer biology, or cell-based therapies.

Work Arrangement

On-site

Team

Structure: Eumbody Group (EBG)

Additional Information

  • You MUST already be located in Japan.
  • Proficiency in English (written and spoken); Japanese language skills are a plus but not required.
Required Skills
molecular biology or cell culture technia research laboratory environmentbasic mammalian cell culture. molecular biology or cell culture technia research laboratory environmentbasic mammalian cell culture.
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About company
Optieum Biotechnologies

Optieum is driving the evolution of next-generation CAR-T cell therapy with precision-engineered CAR constructs. The company's CAR discovery engine focuses on optimizing the binding domain of CAR to enhance immune cell function, delivering robust therapeutic efficacy.

Through its core platform technology, the Eumbody System, Optieum utilizes empirical methodologies to identify optimized CARs, accelerating the development of advanced CAR-T cell therapies. This approach dynamically harmonizes scFv sequences via empirical evaluation, significantly enhancing the functional capabilities of T cells.

The company is focused on pushing the boundaries of solid tumor treatment using next-generation CAR constructs engineered to achieve the optimal activation threshold for T-cells. These constructs demonstrate superior proliferative capacity, prevent antigen escape, and exhibit exceptional reactivity against advanced tumor profiles.

Optieum’s pipeline includes programs targeting FAPa for solid tumors, CD19 for hematological malignancies and autoimmune disorders, and an undisclosed discovery program.

All jobs at Optieum Biotechnologies Visit website
Job Details
Department Eumbody Group
Category other
Posted 3 months ago