Måløv, Hovedstaden, Denmark

Novo Nordisk is hiring a Principal Scientist

Responsibilities

  • Set and execute the Digital Strategy for peptide projects and engage in portfolio initiatives, translating scientific vision into delivery.
  • Lead a team of excellence delivering consolidated in‑silico support to incretin and amylin peptide projects, integrating modelling with unique insights from molecular pharmacology, biophysics and structural biology.
  • Partner with modelling and AI scientists to expand and apply our in‑silico toolbox for innovative, data‑driven decision‑making from ideation to discovery.
  • Contribute to project ideation and assessment, identifying and maturing initiatives that are well suited to peptide modalities for target modulation.
  • Mentor and grow peptide modelling talent and shape best practices for in silico work and multidisciplinary collaboration scenarios.

Requirements

  • PhD in Computational Chemistry, Computational Biophysics, Medicinal Chemistry, or a closely related field.
  • Proven “drug hunter” track record delivering measurable impact via compound optimization within mixed in silico and experimental teams.
  • Deep understanding of the research value chain and assay data relevant to molecular pharmacology, biophysics, and structural biology.
  • Broad in silico expertise: SAR analysis, structure-based modelling, and application of machine learning in drug discovery.
  • Strong coding skills and familiarity with software development best practices and tools (e.g., Python, Git/GitHub).

Nice to Have

  • Experience building computational peptide design platforms, mentoring cross-disciplinary teams or training programs, and familiarity with cloud computing and reproducible in silico workflows.

Benefits

  • Make a direct impact on patients while shaping the digital strategy for a portfolio of peptide programs. You’ll collaborate with senior scientific leaders, supported by rich data, state-of-the-art experimental capabilities, and dedicated AI/modelling partners. Expect an inclusive, collaborative culture with global development opportunities and flexibility where the role allows.

Team

Structure: In Silico Peptide Discovery team, part of Digital Chemistry and Design

Additional Information

  • You only need to submit you CV including a few sentences about why you are applying. To ensure an efficient and fair recruitment process, please refrain from adding a photo in your CV.
  • We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.
Required Skills
Cloud Computing
About company
Novo Nordisk
A healthcare company focused on finding solutions to defeat serious chronic diseases and promote long-term health. For over 100 years, they have approached their work with an unconventional spirit, determination, and curiosity to push the boundaries of science, make healthcare more accessible, and treat, prevent, and cure diseases affecting millions.
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Job Details
Department Research and Development (R&D)
Category other
Posted 4 months ago