The Gladstone-UCSF Institute of Genomic Immunology at the University of California, San Francisco (UCSF) is seeking a Staff Research Associate. In this role, you will assist and potentially lead collaborative cellular engineering projects focusing on fundamental T cell immunology. You will develop novel genetic and epigenetic tools to reprogram primary human immune cells for therapeutic applications.
What You'll Do
- Assist with research using CRISPR engineering tools, genetic and epigenetic screens, and novel cell and gene therapy manufacturing strategies.
- Conduct experiments under the guidance of senior laboratory members.
- Perform data analysis and interpretation.
- Present findings to laboratory members and collaborators.
- Participate in the design and execution of new research projects.
- Assist with the training and supervision of undergraduate students.
What We're Looking For
- A Bachelor’s degree in a related scientific discipline.
- Two years of experience in human CAR-T or TCR-T cell engineering using viral and CRISPR/Cas9 non-viral approaches.
- Two years of experience with flow cytometry, molecular cloning, and mammalian cell culture.
- At least six months of experience with bioinformatics approaches, including basic proficiency with R or Python.
Nice to Have
- A degree in Molecular Biology, Genetics, Bioengineering, Immunology, or a closely related field.
- Prior relevant laboratory experience, especially in immunology, synthetic biology, genome and epigenome engineering, or cell and gene therapies.
- Experience with techniques like PCR, qPCR, cloning, gene editing, cell culture, flow cytometry, and next-generation sequencing.
- Hands-on experience with immunology techniques, including immune cell isolation and multi-color flow cytometry.
- Experience with cell therapy techniques, such as T-cell engineering, stem cell manipulation, or CAR-T cell development.
- Familiarity with bioinformatics tools and data analysis software.
- Excellent interpersonal and communication skills.
Technical Stack
- CRISPR engineering tools
- Genetic and epigenetic screens
- Cell and gene therapy manufacturing
- Flow cytometry
- Molecular cloning
- Mammalian tissue culture
- Bioinformatics (R/Python)
- Viral and non-viral T cell engineering
Team & Environment
You will work directly with graduate students, post-doctoral students, and other laboratory members in a collaborative research setting.
Benefits & Compensation
- Hourly Rate: $28.04 - $45.09
- A stimulating and supportive work environment.
- Ample opportunities for professional development and career advancement.
- A commitment to PRIDE values: Professionalism, Respect, Integrity, Diversity, and Excellence.
- A commitment to equity in healthcare delivery and workforce.
Work Mode
This is an onsite position located in San Francisco, CA.
The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.
