The Gladstone-UCSF Institute of Genomic Immunology at the University of California, San Francisco (UCSF), is hiring a Staff Research Associate. In this role, you will support and potentially lead collaborative cellular engineering projects focused on fundamental T cell immunology. You will help develop novel genetic and epigenetic tools to reprogram primary human immune cells for therapeutic applications in cancer, infectious disease, and autoimmunity.
What You'll Do
- Assist with research using CRISPR engineering tools, genetic and epigenetic screens, and novel cell and gene therapy manufacturing strategies.
- Conduct experiments under the guidance of senior laboratory members.
- Perform data analysis and interpretation.
- Present findings to laboratory members and collaborators.
- Participate in the design and execution of new research projects.
- Assist with training and supervising undergraduate students.
What We're Looking For
- A Bachelor’s degree in a related scientific discipline.
- Two years of experience in human CAR-T or TCR-T cell engineering using viral and CRISPR/Cas9 non-viral approaches.
- Two years of experience with flow cytometry, molecular cloning, and mammalian cell culture.
- At least six months of experience with bioinformatics approaches, including basic proficiency with R or Python.
Nice to Have
- A degree in Molecular Biology, Genetics, Bioengineering, Immunology, or a related field.
- Prior relevant laboratory experience, preferably in immunology, synthetic biology, genome and epigenome engineering, cell and gene therapies, or a related field.
- Experience with molecular and cellular biology techniques, such as PCR, qPCR, cloning, gene editing, cell culture, flow cytometry, and next-generation sequencing.
- Hands-on experience with immunology techniques, including immune cell isolation and multi-color flow cytometry.
- Experience with cell therapy techniques, such as T-cell engineering, stem cell manipulation, or CAR-T cell development.
- Familiarity with bioinformatics tools and data analysis software.
- Excellent interpersonal and communication skills.
Technical Stack
- CRISPR engineering tools
- Flow cytometry
- Molecular cloning
- Mammalian tissue culture
- Viral and non-viral T cell engineering
- R, Python
- Bioinformatics tools
Team & Environment
You will work directly with graduate students, post-doctoral students, and other laboratory members.
Benefits & Compensation
- Hourly rate: $28.04 - $45.09.
- A stimulating and supportive work environment.
- Ample opportunities for professional development and career advancement.
- A commitment to professionalism, respect, integrity, diversity, and excellence (PRIDE values).
- A commitment to equity in care delivery and workforce.
Work Mode
This is an onsite position located in San Francisco, CA.
The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.
