Autoscience is hiring a Senior or Staff Software Engineer (Technical Lead) to build the core systems that power autonomous research agents. This is a full-time on-site role in the San Francisco Bay Area. You will lead the development of reliable backend infrastructure and production systems that support large-scale AI experimentation and research workflows.
What You'll Do
- Lead the design and implementation of core backend and infrastructure systems
- Own projects from architecture and design through production deployment
- Write clear technical design documents and drive engineering decisions
- Build and maintain 24/7 production systems supporting autonomous research agents
- Partner closely with research teams to productionize experimental workflows
- Guide and collaborate with engineers on system design and implementation
- Improve system reliability, scalability, and observability
- Help shape the technical direction of the platform
What We're Looking For
- Experience leading complex engineering projects or technical initiatives
- Experience acting as a technical lead or guiding small teams of engineers
- Strong software design and architecture skills
- Demonstrable experience writing clear technical design documents
- Strong experience with Python
- Experience building or operating backend or production infrastructure
- Experience working in 24/7 production environments
- Experience with Google Cloud Platform (GCP) or similar cloud infrastructure
- Strong understanding of software evolution, maintainability, and system design tradeoffs
- Ability to collaborate effectively with both engineers and researchers
- Bachelor’s degree in Computer Science, Mathematics, or a related field
- 5+ years of experience building and operating production software systems, including ownership of projects from design through deployment
Technical Stack
- Python
- Google Cloud Platform (GCP)
Team & Environment
You will work closely with both engineers and researchers to translate experimental ideas into robust production systems. We're a team of passionate researchers and engineers working to automate scientific discovery.
Work Mode
This is a full-time on-site role located in the San Francisco Bay Area.
We believe in the power of AI to accelerate scientific discovery and are committed to responsible AI development.




