The Senior Scientist will join the Translational Immunology group in Gaithersburg, MD, within the Early Vaccines and Immune Therapies division. This position centers on designing and interpreting mechanistic and translational studies to evaluate vaccine-induced cellular immunity, supporting the progression of vaccine programs from preclinical to clinical development.
Responsibilities
- Design and perform in vitro experiments to measure vaccine-specific cellular immune responses and apply findings to improve vaccine technologies for cancer and infectious diseases.
- Create, refine, and implement novel assays to detect and quantify cellular targets and efficacy indicators linked to vaccine performance.
- Keep up with advances in immunology, oncology, and vaccinology by reviewing scientific literature and emerging platforms, and share knowledge across the Early Vaccines and Immune Therapies teams.
- Assess new technologies and assay formats for evaluating human immune function to promote innovation and continuous improvement.
- Present findings in team and departmental meetings and represent the group at scientific conferences.
- Maintain accurate electronic records and ensure all work adheres to Good Laboratory Practice (GLP), Safety, Health and Environment (SHE) standards, and applicable internal and external regulations.
Requirements
- Ph.D. in Immunology or a closely related scientific field.
- Minimum of three years of post-doctoral or industry experience in relevant disciplines.
- Demonstrated expertise in immunology through publications and applied research in infectious disease and tumor-immune interactions.
- In-depth knowledge of tumor biology, immune oncology methods, and experimental model systems.
- Extensive hands-on experience with multi-color flow cytometry, including panel design, staining, compensation, and data analysis.
- Proficient in functional cell-based assays to assess therapeutic mechanisms such as cytotoxicity, T/NK cell activation, and cytokine production.
- Comprehensive experience with single-cell RNA sequencing (scRNA-seq), CITE-seq, and ATAC-seq, including experimental design, library preparation, quality control, and data interpretation.
- Proven track record in developing, validating, and troubleshooting assays, as well as evaluating novel therapeutic approaches.
- Strong ability to collaborate across functions, communicate clearly, and work effectively in team environments with discovery, translational, and data science teams.
Tech Stack
flow cytometry, multi-color flow cytometry, cell-based assays, scRNA-seq, CITE-seq, ATAC-seq, GLP, SHE
Benefits
- Eligibility for short-term incentive bonus
- Equity-based long-term incentive program for salaried roles
- Retirement contribution for hourly roles
- Commission payment eligibility for sales roles
- Qualified retirement savings plan (401(k))
- Paid vacation and public holidays
- Paid leave options
- Comprehensive health benefits including medical, prescription drug, dental, and vision coverage
Compensation
Annual base salary between $112,304.00 and $168,456.00 USD. Eligible for equity-based long-term incentives (salaried roles), short-term bonus, retirement contributions (hourly roles), and commission (sales roles).
Work Arrangement
Hybrid work model in Gaithersburg, MD, requiring a minimum of three days per week in the office, with flexibility allowed.
Team
Part of the Translational Immunology group within the Early Vaccines and Immune Therapies division.
- Driven by a mission to transform global healthcare
- Committed to pandemic preparedness
- Fosters collaboration and groundbreaking partnerships
- Supports a diverse community that encourages idea exchange
- Invests in advanced technologies for next-generation vaccine development
Additional Information
- This position is at-will employment.
- The company reserves the right to adjust base pay based on individual performance, team performance, and market conditions.
- Work location is Gaithersburg, MD.
- Job posting date: 10-Mar-2026
- Application closing date: 23-Mar-2026
- Equal employment opportunity is provided to all applicants and employees without regard to protected characteristics.
- Accommodations are available for applicants with disabilities or special needs.
