Revolution Medicines is looking for a Senior Scientist I to join its Clinical Biomarker Development team within Translational Medicine. In this role, you will play a key part in designing, executing, and interpreting clinical biomarker strategies across the company's oncology pipeline, supporting our commitment to patients with cancers driven by mutations in the RAS signaling pathway.
What You'll Do
- Design and execute clinical biomarker strategies to support early response monitoring, patient stratification, and understanding resistance mechanisms.
- Support biomarker implementation for early- and late-stage oncology clinical trials.
- Oversee biomarker assay development, qualification, and sample analysis in collaboration with internal teams and external CROs.
- Analyze and interpret biomarker data in the context of clinical outcomes and present results to cross-functional teams.
- Contribute to clinical protocols, study reports, and regulatory documents such as INDs, IBs, and CSRs.
- Translate preclinical findings into clinically actionable biomarker hypotheses.
- Stay current with emerging biomarker technologies and trends in precision oncology.
What We're Looking For
- PhD in a relevant scientific discipline with 3+ years of relevant industry experience in clinical biomarkers, translational medicine, or related roles.
- Experience supporting oncology clinical trials with biomarker components.
- Familiarity with biomarker platforms such as genomic/molecular and proteomic assays.
- Experience working with CROs and managing external vendors.
- Strong scientific communication skills and ability to work cross-functionally.
Nice to Have
- Experience with targeted oncology therapies or RAS/MAPK pathway biology.
- Biological understanding of pancreatic, non small cell lung, and/or colorectal cancers.
- Familiarity with analytical software for data analysis and interpretation.
Team & Environment
You will be part of the Clinical Biomarker Development team within the Translational Medicine organization.
Benefits & Compensation
- Salary range: $149,000—$186,000 USD
Work Mode
This is a hybrid position based in Redwood City, CA.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.



