Revolution Medicines is hiring a Senior Safety Scientist to join our Global Patient Safety Science team. You will provide critical drug safety and pharmacovigilance support across our full portfolio of early and late-phase development products. This individual contributor role involves direct safety oversight of clinical studies and active participation in cross-functional teams dedicated to our mission of addressing cancers with mutations in the RAS signaling pathway.
What You'll Do
- Perform proactive medical safety surveillance of ongoing clinical trials to identify and manage safety signals.
- Prepare and present safety data summaries to internal and external stakeholders.
- Conduct risk management activities including medical review of individual case safety reports (ICSRs) and routine review of safety data.
- Acquire and contribute knowledge of relevant drug class and competitor safety issues.
- Identify potential clinical safety issues and recommend appropriate risk mitigation measures.
- Contribute to the preparation and maintenance of key documents including clinical trial protocols, Investigator's Brochures (IBs), DSURs, RMPs, and labeling.
- Perform safety review of clinical protocols, informed consent forms (ICFs), and other related documents.
- Own the safety components of study reports (CSRs), publications, aggregate reports, and other regulatory documents.
- Conduct signal detection and evaluation activities for assigned products for continuous benefit-risk assessment.
- Support the implementation of decisions from the signal evaluation process.
- Contribute to input for regulatory filings (NDAs, BLAs) and responses to safety queries from regulatory agencies.
- Establish and maintain collaborative working relationships with all key stakeholders including study teams, CROs, and investigators.
- Consistently comply with all governing laws, regulations, and company standard operating procedures.
What We're Looking For
- A relevant postgraduate qualification such as an MD, PharmD, PhD, or MSc in a Life Sciences discipline.
- 3 or more years of drug development experience in the pharmaceutical industry with at least 1 year specifically in drug safety.
- Proven success in creating and sustaining strong relationships with internal and external business partners.
- Broad understanding of the scientific aspects of safety, pharmacovigilance (including GVP, GCP), and clinical risk management.
- Demonstrated ability to lead and influence, with and without authority, in a fast-paced environment.
- Strong presentation skills, effective at summarizing and presenting key considerations and decision points.
- Ability to thrive in a collaborative team setting and a desire to deploy innovative approaches.
- Detail-oriented with the ability to prioritize tasks and function independently as appropriate.
- Strong organizational skills and an ability to interpret, discuss, and report trial-level data effectively.
- Excellent written and verbal communication skills.
Team & Environment
You will be an individual contributor within the Global Patient Safety Science function, working cross-functionally with development teams.
Benefits & Compensation
- Competitive cash compensation ranging from $164,000—$205,000 USD.
- Robust equity awards.
- Comprehensive benefits package.
- Significant learning and development opportunities.
Work Mode
This role follows a hybrid work model and is based in Redwood City, CA.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
