Scientist II – Biological Research and Development
Role Summary
This position supports the development and manufacturing of commercial biological toxin therapeutics through advanced scientific investigation and process innovation. Based in Irvine, CA, the Scientist II applies deep technical expertise in molecular and cellular biology to ensure product quality, scalability, and regulatory compliance.
Key Responsibilities
- Design, program, and maintain robotic liquid handling systems—including Hamilton STAR and Opentrons platforms—to enable high-throughput testing and streamline laboratory workflows.
- Lead experimental design and interpretation, applying scientific rigor to generate reproducible data for drug substance and product release and stability programs.
- Develop and refine bioassays and laboratory protocols using emerging technologies and current scientific best practices.
- Drive technical problem-solving by integrating new data into evolving research strategies and adapting approaches in response to project needs.
- Apply expertise in molecular cloning, mammalian cell culture, PCR, Western blot, protein expression, purification, and transfection to support assay development and validation.
- Ensure scientific accuracy and regulatory compliance by authoring and reviewing SOPs, technical reports, and submissions.
- Communicate findings clearly to cross-functional teams through written documentation and oral presentations.
- Manage project timelines and experimental progress to meet critical milestones efficiently.
Qualifications
Successful candidates will have extensive hands-on experience in core laboratory techniques including molecular cloning, cell culture, PCR, protein analysis, bioassay development, and transfection. Proficiency with laboratory automation systems is essential. The role requires strong scientific judgment, organizational ability, and the capacity to collaborate effectively across disciplines. Excellent written and verbal communication skills are required to support knowledge sharing and regulatory documentation.
