BeOne Medicines seeks a Director, Global Health Economic & Outcomes Research / Real World Evidence (HEOR/RWE lead – BTK Degrader) to provide strategic leadership for evidence generation supporting a novel therapeutic program. You will develop and execute integrated value evidence strategies across development, launch readiness, and lifecycle management to meet medical, regulatory, commercial, and reimbursement needs in key global markets.
What You'll Do
- Lead global HEOR/RWE strategy and evidence generation activities for the BTK degrader asset across its full lifecycle.
- Develop and execute integrated value evidence generation plans, covering disease burden, treatment patterns, comparative effectiveness, indirect comparisons, economic modeling, and patient-centered outcomes.
- Design and execute real-world evidence and comparative effectiveness studies using various data sources including claims and electronic health records.
- Collaborate on JCA/HTA submissions and lead key HEOR deliverables, including indirect comparisons and economic modeling.
- Lead development of Global Value Dossiers and US AMCP dossiers to support reimbursement submissions.
- Lead development of health economic models, including cost-effectiveness and budget impact analyses.
- Drive scientific dissemination of HEOR/RWE evidence through abstracts, manuscripts, congress presentations, and omnichannel distribution.
- Partner cross-functionally with Clinical Development, Biostatistics, Medical Affairs, Regulatory, Commercial, and Market Access teams.
- Manage external vendors and research partners, overseeing study design, project execution, deliverables, timelines, and budgets.
- Provide strategic HEOR guidance to affiliates and regional teams to support local evidence needs.
What We're Looking For
- Advanced degree in Health Economics Outcomes Research (HEOR), Epidemiology, Public Health, Biostatistics, or a related discipline.
- PhD with 5+ years or Master’s degree with 7+ years of related experience in the biopharmaceutical industry or consulting.
- Strong understanding of market dynamics and reimbursement landscapes, with experience supporting HTA and/or JCA submissions.
- Proven success leading and executing evidence generation strategies and HEOR deliverables.
- Demonstrated research expertise in designing and conducting HEOR/RWE studies, including indirect comparisons, economic models, and comparative effectiveness studies.
- Impactful communication and presentation skills, with the ability to translate complex data and engage diverse stakeholders.
- Highly organized and self-motivated with the ability to effectively prioritize and manage multiple projects, timelines, and budgets.
- Ability to work in a cross-functional matrix team environment and collaborate effectively with internal and external stakeholders.
Nice to Have
- Hematology/Oncology experience strongly preferred.
- Innovative thinking and a creative mindset with applied AI understanding to enhance evidence generation and HEOR insights.
Technical Stack
- Microsoft Office
- Statistical software
- HEOR modeling tools
- AI
Team & Environment
This role is a key cross-functional partner to medical, commercial, clinical development, and regulatory teams.
Benefits & Compensation
- Compensation range: $185,300 - $245,300 annually.
- All employees are eligible for discretionary equity awards.
- Medical, Dental, Vision, Life Insurance
- 401(k), FSA/HSA
- Paid Time Off, Wellness programs
- Eligibility for Employee Stock Purchase Plan
- Non-Commercial roles eligible for annual bonus plan; Commercial roles eligible for incentive compensation plan
We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law.
