Crinetics Pharmaceuticals is looking for a Senior Director, Clinical Science to lead a team of Clinical Scientists executing our Endocrine Clinical Development programs. You will provide crucial clinical and scientific insights to support all phases of our clinical studies and collaborate deeply with cross-functional partners.
What You'll Do
- Lead and mentor the Clinical Scientist team, including consultants, by reviewing their work and supporting their professional growth.
- Serve as a key scientific link between clinical research and other departments including clinical operations, regulatory, biostatistics, pharmacovigilance, and medical affairs.
- Support data cleaning and analyses for clinical studies to enable high-quality medical decision making, presentations, manuscripts, and regulatory documents.
- Collaborate with Medical Monitors, biometrics, and pharmacovigilance to review periodic data listings and perform systematic evaluations of clinical data for quality and trends.
- Participate in Medical Review meetings and contribute to trial-related advisory boards, investigator meetings, and protocol training.
- Contribute to the development of regulatory documents such as protocols, amendments, briefing books, and safety updates.
- Develop study documents including feasibility questionnaires, study plans, electronic Case Report Forms (eCRFs), and eCRF guidelines.
- Collaborate in cross-functional meetings to help shape clinical development plans.
- Support Clinical Operations, CROs, and site staff on protocol-related questions and preparations for safety review committees.
- Help build effective relationships with key investigators and opinion leaders and participate in research site identification.
What We're Looking For
- An MD, Ph.D., Pharm.D., MPH, MS, Bachelor’s degree in Biological Sciences, or RN.
- A minimum of 15-20 years of clinical research experience in clinical development (Phase 1 to 3) within a biopharmaceutical company.
- At least 5 years of experience in the Endocrine therapeutic area and in rare disease clinical development.
- A proven track record of contributing meaningfully to the design, execution, and analysis of phase 1-3 clinical trials.
- Working knowledge of FDA and EMA regulations, Good Clinical Practice, ICH guidelines, and clinical drug development.
- Practical, hands-on knowledge of day-to-day clinical trial activities.
- Excellent analytical skills and attention to detail, with effective and collaborative writing abilities.
- Ability to build and maintain strong interpersonal relationships and inspire respect from leadership, colleagues, and staff.
- Capacity to thrive in a fast-paced, dynamic, entrepreneurial environment and to prioritize multiple workstreams.
- High ethical standards and integrity.
Team & Environment
You will work within a multi-disciplinary team and lead a group of Clinical Scientists, contributing to our patient-centric and team-oriented culture.
Benefits & Compensation
- Compensation range: $250,000 - $287,000
- Discretionary annual target bonus
- Stock options and ESPP
- 401k match
- Top-notch health insurance plans (medical, dental, vision, basic life) for employees and their families
- 20 days of PTO and 10 paid holidays
- A winter company shutdown
Work Mode
This is an onsite position located in San Diego, California.
Crinetics is proud to be an Equal Opportunity Employer, providing equal employment opportunities to all employees and applicants without regard to sex, sexual orientation, gender, pregnancy, race, color, creed, national origin, citizenship, religion, disability, marital status, age, genetic information, veteran status, or any other protected characteristic.
