Landmarkbio is hiring a Scientist, Process Development to play a key role in planning and executing upstream cell culture process experiments, analyzing data, and contributing to process development projects. You will apply your expertise in cell culture and continuous manufacturing to troubleshoot complex issues.
What You'll Do
- Execute all aspects of mammalian cell culture using aseptic technique.
- Culture different cell types including primary cells, cell lines, and iPSC cells.
- Maintain small-scale bioreactors from 0.25mL to 10L scale in perfusion mode.
- Perform cell transfection, transduction, and other genetic manipulation techniques.
- Develop unit operations suitable for integration in a continuous manufacturing process.
- Maintain accurate and reliable records including database management, batch records, and lab notebooks.
- Write and/or contribute to SOPs, batch records, protocols, and reports.
- Cross train and collaborate with colleagues on harvest and downstream purification technologies.
- Comply with all environmental health and safety standards.
- Follow a flexible schedule based on experimental work, which may require some weekend hours.
What We're Looking For
- Ph.D. in chemical engineering, biology, biotechnology, or a related discipline; or a Master’s degree with 5+ years or a Bachelor’s degree with 8+ years of relevant experience.
- Strong understanding of tissue culture and aseptic technique.
- Experience working with bioreactors in perfusion mode.
- A strong team worker who is also independently motivated, detail-oriented, and possesses good problem-solving capabilities.
- Demonstrated ability to work both independently and as part of an interdisciplinary team.
- Excellent organizational skills.
- Strong verbal and written skills; able to handle confidential information appropriately.
Nice to Have
- A track record of success in biopharmaceutical process development.
- Experience with continuous biomanufacturing process development.
- Experience with scale-up and scale-down of perfusion cell culture processes.
- Experience or knowledge of extracellular vesicle process development.
Technical Stack
- Perfusion bioreactors
- Mammalian cell culture
- Aseptic technique
- Cell transfection
- Cell transduction
Work Mode
This is an onsite position located in Watertown, Massachusetts.
Landmark Bio is an Equal Opportunity, Affirmative Action employer. Minorities, women, veterans, and individuals with disabilities are encouraged to apply.
