Landmark Bio is seeking a Scientist to execute our Analytical Sciences strategy. You will work in a cross-functional, collaborative environment to directly support the development and cGMP manufacturing of cutting-edge cell and gene therapies.
What You'll Do
- Apply analytical and biophysical characterization techniques including flow cytometry, nanoflow cytometry, ELISA, qPCR/ddPCR, and protein analytics.
- Develop analytical assays specifically for cell and gene therapy products.
- Lead assay qualification and tech transfer activities to QC.
- Perform general laboratory tasks, including the maintenance and troubleshooting of equipment.
- Maintain accurate and reliable records, including database management, lab notebooks, and all pertinent documentation.
- Write and/or contribute to protocols, test methods, and reports.
- Comply with all environmental health and safety standards.
- This is a hands-on, lab-based position requiring a flexible schedule based on experimental demands.
What We're Looking For
- A Ph.D. in chemical engineering, biology, biotechnology, or a related discipline; or a Master’s degree with 5+ years of relevant experience; or a Bachelor’s degree with 8+ years of relevant experience.
- A strong team player who is also independently motivated, detail-oriented, and possesses excellent problem-solving capabilities.
- A demonstrated ability to work both independently and as part of an interdisciplinary team.
- Excellent organizational skills.
- Strong verbal and written communication skills, with the ability to handle confidential information appropriately.
Nice to Have
- A PhD with 2+ years or an MS with 8+ years of work experience in cell and gene therapy or a related field.
- Experience using protein and genome-based techniques such as nanoparticle characterization, gel electrophoresis, western blotting, capillary electrophoresis, flow/nanoflow cytometry, ELISA, and qPCR/dPCR/ddPCR.
- Experience or knowledge in physically, chemically, and biologically characterizing extracellular vesicles.
- Experience supporting in-process characterization, method transfer, and release testing of drug substance and drug products.
- Experience in multiple aspects of aseptic mammalian cell culture, cell enumeration, and phenotypic characterization.
Technical Stack
- Flow cytometry & nanoflow cytometry
- ELISA
- qPCR & ddPCR
- Protein analytics
- Nanoparticle characterization
- Gel electrophoresis, western blotting, capillary electrophoresis
- Aseptic mammalian cell culture
Work Mode
This is an onsite position.
