Gilead Sciences is looking for a Senior Scientist, Biomarker - Oncology to provide scientific leadership for our Oncology pipeline. You will focus on tumor biology integrated with immunology, creating and executing high-quality integrated discovery and translational plans for preclinical and clinical programs.
What You'll Do
- Lead cross-functional Biomarker Teams to define and execute biomarker and diagnostic development strategies for clinical studies.
- Direct the development, outsourcing, and validation of clinically applicable biomarker assays including pharmacodynamic, predictive, prognostic, and safety biomarkers.
- Identify, establish, and oversee external collaborations with key opinion leaders, academic sites, and CROs to advance understanding of disease pathways.
- Collaborate with Research Biology, Clinical Development, Diagnostics, Bioinformatics, and Biostatistics functions to create synergy in biomarker strategies.
- Write, review, and coordinate biomarker plans in clinical trial protocols, regulatory documents, and collaboration agreements.
- Work independently and effectively on multiple programs in a fast-paced matrixed environment.
- Design and implement translational research plans leveraging clinical samples, multi-omic profiling, spatial biology, and functional assays to uncover mechanisms of response, resistance, and disease evolution.
What We're Looking For
- High School Degree and Twelve Year's Experience OR
- Associates Degree and Ten Years Experience OR
- Bachelor's Degree and Eight Years’ Experience OR
- Masters' Degree and Six Years’ Experience OR
- Ph.D.
Nice to Have
- Ph.D. and/or post-doctoral training in immunology, oncology, or related field with 5+ years of industry experience (7+ years preferred).
- Detail-oriented with excellent record keeping and organizational skills.
- Highly flexible, results-oriented, independent self-starter who thrives in a fast-paced dynamic environment.
- Experience planning and executing biomarker and diagnostic strategy, experimentation, and testing in support of drug discovery and development.
- Experience authoring biomarker strategy documents, clinical protocol sections, and regulatory documentation.
- Demonstrates technical proficiency, scientific creativity, and independent thought in suggesting biomarker strategies for immunology and/or oncology.
- In-depth knowledge of biomarker discovery, assay development and validation, translational research, and companion diagnostics.
- Understanding of the opportunities and challenges in implementing biomarker technologies in preclinical and clinical settings.
- Experience analyzing high-content NGS data and other human datasets to define therapeutic mechanisms and patient enrichment strategies.
- Proven track record in effectively applying original scientific thought to project concepts.
- Proven scientific and leadership expertise in team environments.
- Strong track record of high-quality publications.
- Strong communication and organizational skills, with an ability to lead, influence, and motivate others.
- When needed, ability to travel.
Technical Stack
- Genomic, epigenetic, and gene expression analysis
- Metabolomics and multiplexed protein detection
- NGS data analysis
Team & Environment
Dynamic multidisciplinary matrixed team environment within a highly matrixed organization.
Benefits & Compensation
- Salary range: $169,320.00 - $219,120.00
- Discretionary annual bonus
- Discretionary stock-based long-term incentives
- Paid time off
- Company-sponsored medical, dental, vision, and life insurance plans
Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences.
