The ovarian cancer research laboratory at the University of Chicago, led by Drs. Hilary Kenny and Ernst Lengyel, is seeking a Staff Scientist with expertise in bottom-up proteomics to advance plasma and spatial proteomics research. The role involves leading collaborative efforts to optimize proteomics methods and serving as the primary contact for proteomics-related collaborations within the Department of Obstetrics and Gynecology.
What You'll Do
- Train, mentor, and supervise laboratory personnel within the development subgroup, including instruction on new techniques, protocol adherence, and data integrity standards.
- Lead collaborative efforts to optimize proteomics methods, analytical modeling, and data interpretation across multidisciplinary and international partnerships.
- Serve as the primary contact for proteomics-related collaborations, coordinating scientific priorities, troubleshooting technical challenges, and ensuring alignment with project objectives.
- Ensure compliance of all research activities with institutional, state, and federal regulatory requirements, including support for IRB protocols and human subject research standards.
- Serve as a scientific resource for data collection, experimental design, and complex data analysis, providing intellectual and technical expertise to advance project goals.
- Review and refine laboratory protocols, implement new methodologies, and manage complex, high-dimensional research datasets.
- Lead and support scientific writing efforts, including preparation and revision of IRB protocols, peer-reviewed publications, and federal and non-federal grant submissions.
- Contribute to proofreading, fact checking, and scientific editing of manuscripts, grant applications, and professional presentations to ensure accuracy and clarity.
- Perform other related work as needed.
What We're Looking For
- PhD in a related field.
- Knowledge and skills developed through 2-5 years of work experience in a related job discipline.
Nice to Have
- PhD in biochemistry, molecular biology, analytical chemistry, bioinformatics, or a related discipline.
- 3-5 years of hands-on experience with LC-MS/MS systems strongly preferred.
- Experience with LC-MS/MS, bottom-up proteomics, sample preparation (including working with plasma or tissue samples), bioinformatics/data analysis tools, and experimental design strongly preferred.
- Strong academic background with a publication record in peer-reviewed journals strongly preferred.
Technical Stack
- LC-MS/MS systems
- Bottom-up proteomics
- Bioinformatics/data analysis tools
- Microsoft Office applications
- Scientific data management and analysis platforms
Team & Environment
You will join a laboratory of about 15 members within the Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, reporting directly to Principal Investigators Drs. Hilary Kenny and Ernst Lengyel.
Benefits & Compensation
- Competitive salary ranging from $70,000 to $90,000
- Extensive fringe benefits, including supplements for health insurance and retirement
- Structured career development program
Work Mode
This is an onsite position located at the Center for Integrated Science on the University of Chicago campus.
The University of Chicago is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, or expression, national or ethnic origin, shared ancestry, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law.
