Watertown, Massachusetts, United States On-site Employment

Landmark Bio is hiring an Associate Scientist, Process Development

About the Role

Landmark Bio is hiring an Associate Scientist, Process Development to join our team. This hands-on, lab-based role focuses on downstream processing, requiring a strong understanding of purification principles and commitment to collaborative project success.

What You'll Do

  • Plan and execute downstream processing experiments, including purification techniques like affinity and anion exchange chromatography and filtration.
  • Perform general laboratory tasks and equipment maintenance.
  • Maintain accurate and reliable records, including database entries, batch records, and lab notebooks.
  • Write and contribute to SOPs, batch records, protocols, and reports.
  • Cross-train and collaborate with colleagues on upstream production and harvest technologies.
  • Comply with all environmental health and safety standards.
  • Adapt to a flexible schedule based on experimental needs, which may include some weekend work.

What We're Looking For

  • A Bachelor’s degree with 5+ years or a Master’s degree with 3+ years of relevant experience in biology, bioengineering, biotechnology, chemical engineering, or a related field.
  • Hands-on experience with clarification, filtration, and chromatography technologies.
  • A strong team player who is also independently motivated, detail-oriented, and possesses good problem-solving skills.
  • Demonstrated ability to work both independently and as part of an interdisciplinary development team.
  • Excellent organizational skills.
  • Strong verbal and written communication skills; ability to handle confidential information appropriately.

Nice to Have

  • A track record of success in biopharmaceutical process development.
  • Experience using the Unicorn software as part of the AKTA chromatography system.
  • Experience with continuous biomanufacturing process development.
  • Experience with downstream unit operations suitable for continuous manufacturing, such as single pass tangential flow filtration (SPTFF), simulated moving bed chromatography, and/or periodic countercurrent chromatography.
  • Experience or knowledge of extracellular vesicle process development.

Technical Stack

  • Affinity chromatography
  • Anion exchange chromatography
  • Filtration
  • AKTA chromatography system
  • Unicorn software
  • Single pass tangential flow filtration (SPTFF)
  • Simulated moving bed chromatography
  • Periodic countercurrent chromatography

Team & Environment

The role involves cross-training and collaboration with colleagues on upstream production and harvest technologies.

Work Mode

This is an onsite position located in Watertown, Massachusetts.

Landmark Bio is an Equal Opportunity, Affirmative Action employer. Minorities, women, veterans, and individuals with disabilities are encouraged to apply.

Required Skills
affinity chromatographyanion exchange chromatographyfiltrationAKTA chromatography systemUnicorn softwaresingle pass tangential flow filtration (SPTFF)simulated moving bed chromatographyperiodic countercurrent chromatographyprocess developmentbioengineeringchemical engineeringproblem-solving
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About company
Landmark Bio

Landmark Bio is a Watertown, Massachusetts–based company focused on advancing the development and manufacturing of genetic medicines and other advanced therapies. The organization provides CMC development and GMP manufacturing capabilities for cell and gene therapies and works with industry partners to develop scalable manufacturing approaches that help bring new therapies to patients.

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Job Details
Department Research and Development (R&D)
Category other
Posted 14 days ago