Twist Bioscience is hiring a Manager, Antibody Characterization

This is a management position that provides support for bioanalytical characterization for a variety of therapeutic antibody candidates. This role oversees our Antibody Characterization team and is responsible for managing, optimizing, and troubleshooting a range of workflows, including immunoassays, affinity analysis, functional assays, and target binding characterization. ESSENTIAL FUNCTIONS - Lead, manage, and develop a team of scientists and research associates in our Antibody Characterization department. - Provide technical guidance (assay development, analysis, and data reporting) in a range of areas, including high-throughput ELISA, flow cytometry, kinetic assays (BLI and SPR), advanced/custom characterization, and functional screening. - Serve as an end-to-end technical lead for a variety of in vivo antibody discovery programs and contract services, contributing to scientific planning and feasibility review during project scoping. - Review, critically analyze, and present data to customers to facilitate antibody lead selection for a variety of concurrent antibody discovery programs. - Work closely with the Project Management team to communicate timelines and deliverables to internal and external stakeholders and customers. - Work closely with all scientific departments and senior management to ensure excellent management of all activities and effective communication. - Promote operational and scientific excellence by driving continuous process improvement. - Stay up to date with recent developments in antibody discovery methods and technologies, and help guide the advancement of our laboratory capabilities in alignment with strategic company goals. - Spend approximately 30-50% of your time performing wet-lab benchwork alongside the team. POSITION QUALIFICATIONS - PhD in a related technical field with 3+ years of management experience in biopharmaceutical analytical development, or MS with 5+ years of experience, including 3+ years of management experience. - Expert knowledge of biologics characterization assays: extensive hands-on experience required in ELISA, flow cytometry, and SPR/BLI with Carterra and Sartorius Octet. - Very strong track record of developing, executing, and analyzing common assay formats for biologics discovery, such as high-throughput screening, epitope binning, ligand blocking analysis, affinity analysis, and cell-based functional assays. - Able to independently manage and prioritize tasks in a fast-paced environment that hinges on overlapping projects and sensitive workflow timelines. - Advanced understanding of in vivo antibody discovery concepts. - Proven ability to assess, interpret, and present complex scientific data effectively and with a high level of integrity and ethics. - Proven management skills for both projects and people, with a strong track record of building trust and developing teams at a variety of levels. - Exceptional written and verbal communication skills, including customer-facing communication. - Highly organized and detail-oriented with a focused, problem-solving mentality to address projects and logistics.