Howard Hughes Medical Institute (HHMI) is looking for a Bioinformatics Specialist to join the Brown Laboratory. In this role, you will support computational analysis of large-scale biological datasets, focusing on single-cell genomic and spatial transcriptomic data to advance research on immune cell development and function. You will work closely with a collaborative team to design and implement computational workflows for fundamental and translational immunology research.
What You'll Do
- Work collaboratively with research scientists to design and implement computational workflows for analyzing large-scale biological datasets.
- Perform quality control on raw experimental data and preprocess data for downstream analyses.
- Analyze and interpret high-throughput sequencing data using bioinformatics tools and software, including single-cell RNA-seq, scATAC-seq, CUT&Tag, and spatial transcriptomics platforms.
- Apply statistical methods and machine learning approaches to identify patterns and relationships in complex biological datasets.
- Summarize and communicate analytical findings clearly to research team members.
What We're Looking For
- Bachelor’s or Master’s degree in Bioinformatics, Computational Biology, or a related quantitative field.
- Strong programming skills in Python and R.
- Experience analyzing genomic or transcriptomic datasets.
- Experience with commonly used bioinformatics tools and databases.
- Strong analytical and problem-solving abilities.
- Excellent communication and collaboration skills.
- Ability to work effectively within an interdisciplinary research team.
Technical Stack
- Languages: Python, R
- Core Analyses: single-cell RNA-seq, scATAC-seq, CUT&Tag
- Platforms: Spatial transcriptomics platforms (including 10X Xenium, Visium HD)
- General: Bioinformatics tools
Team & Environment
You will join a collaborative team of scientists and trainees within a highly collaborative and intellectually vibrant scientific community. There are frequent opportunities for networking and career development.
Benefits & Compensation
- Compensation range: $104,995.00 (minimum) - $131,300.00 (midpoint) - $170,660.00 (maximum).
- A competitive compensation package with comprehensive health and welfare benefits.
- The opportunity to join the vibrant Tri-Institutional scientific community spanning MSK, Weill Cornell, and Rockefeller University.
- Exposure to advanced immunology and genomic research.
- Opportunities for mentorship, career development, and professional growth.
- Opportunities to contribute to publications and present work at conferences.
Work Mode
This is an onsite position located at 1275 York Avenue, New York, NY, 10021.
HHMI is an Equal Opportunity Employer.





